| |
An integrated pharmacokinetic model for the influence of CYP3A4 expression on the in vivo disposition of lopinavir and its modulation by ritonavir
|
Material Type |
Article
|
Author(s) |
Heine, Rob ter (Author)
Van Waterschoot, Robert A. B (Author)
Keizer, Ron J (Author)
|
Source Journal Info. |
Title:
Journal of Pharmaceutical Sciences
|
|
Volume/ Issue No.: 2011/JUN V.100 N.6
Call No.:615.05 JPS Location: Periodicals & References Hall - 2nd floor
|
Physical Description |
p 2508–2515
|
Subject Area/ Descriptors |
Medical sciences
(12461)
|
|
|
Abstract |
Lopinavir, a human immunodeficiency virus protease inhibitor, has a very low oral bioavailability, which can be enhanced with a low dose of the CYPA4 inhibitor ritonavir....
Full Abstract
|
| More Articles from:
Journal:
Journal of Pharmaceutical Sciences
(785)
Issu: 2011/JUN V.100 N.6
|
|
|
|
| |
|
Search Through eResources |
● |
● |
Related topics |
|
|
|
|