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Publication type: Article
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| Title: |
An integrated pharmacokinetic model for the influence of CYP3A4 expression on the in vivo disposition of lopinavir and its modulation by ritonavir
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| Author(s): |
Heine,Rob ter
(Author)
Van Waterschoot,Robert A. B
(Author)
Keizer,Ron J
(Author)
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| Source Journal Info. |
Title:Journal of Pharmaceutical Sciences
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Issue Number:2011/JUN V.100 N.6
Call No.:615.05 JPS
Location: References & Periodical Hall - 2nd floor
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| Physical Description: |
p 2508–2515
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| Subject Area: |
Medical sciences
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| Subject Terms: |
Pharmacy
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| Accession Number |
145531
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Abstract
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Lopinavir, a human immunodeficiency virus protease inhibitor, has a very low oral bioavailability, which can be enhanced with a low dose of the CYPA4 inhibitor ritonavir. ...
Abstract URL:http://onlinelibrary.wiley.com/doi/10.1002/jps.22457/abstract
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