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Publication type: Article
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Title: |
Improved Sensitivity of a Dual-Target HIV-1 Qualitative Test for Plasma and Dried Blood Spots
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Author(s): |
Templer,Stefanie P.
(Author)
Seiverth,Britta
(Author)
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Source Journal Info. |
Title:Journal of Clinical Microbiology
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Issue Number:2016/JUL V.54 N.7
Call No.:616.0105 JCM Location: References & Periodical Hall - 2nd floor
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Physical Description: |
p 1877-1882
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Subject Area: |
Medical sciences
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Subject Terms: |
Pharmacy
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Accession Number |
154486
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Abstract
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The use of nucleic acid detection for HIV type 1 (HIV-1) detection is strongly recommended in infants <18 months of age, in whom serology is unreliable. This study evaluated the Cobas AmpliPrep/Cobas TaqMan HIV-1 Qualitative Test v2.0 (TaqMan HIV-1 Qual Test, v2.0), a dual-target total nucleic acid real-time PCR assay. The limit of detection (LOD) of the new test in plasma and dried blood spots (DBS) was determined with the 2nd International HIV-1 RNA WHO standard. The specificity of the assay was tested with EDTA plasma (n = 1,301) and DBS from HIV-negative adults (n = 1,000). ...
Abstract URL:http://jcm.asm.org/content/54/7/1877.abstract
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