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         Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency
 

 
Author   Cruz,Joao C. S. (Author)
Journal Title   Journal of Natural Products
Volume/ Issue   2015/NOV V.78 N.11
Physical Description   p 2642–2647
Subject Area   Chemistry
Abstract   We identified an Actinoallomurus strain producing NAI-107, a chlorinated lantibiotic effective against multidrug-resistant Gram-positive pathogens and previously reported from the distantly related genus Microbispora. Inclusion of KBr in the production medium of either the Actinoallomurus or the Microbispora producer readily afforded brominated variants of NAI-107, which were designated as NAI-108.... | View Full Abstract
Subject Headings   Natural products
Call Number   547.005 JNP
Location   Periodicals Hall 2nd floor - قاعة الدوريات - الطابق الثاني

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