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Publication type: Article
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| Title: |
Expanding the Chemical Repertoire of the Endophyte Streptomyces albospinus RLe7 Reveals Amphotericin B as an Inducer of a Fungal Phenotype
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| Author(s): |
Chagas,Fernanda Oliveira
(Author)
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| Source Journal Info. |
Title:Journal of Natural Products
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Issue Number:2017/MAY V.80 N.5
Call No.:547.005 JNP
Location: References & Periodical Hall - 2nd floor
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| Physical Description: |
p 1302–1309
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| Subject Area: |
Chemistry
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| Subject Terms: |
Natural products
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| Accession Number |
161118
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Abstract
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During an investigation of the chemistry of the endophytic actinobacterium Streptomyces albospinus RLe7, which was isolated from the roots of the Brazilian medicinal plant Lychnophora ericoides, three new natural products, (2R*,4S*)-2-((1?S*)-hydroxy-4?-methylpentyl)-4-(hydroxymethyl)butanolide (1), (3R*,4S*,5R*,6S*)-tetrahydro-4-hydroxy-3,5,6-trimethyl-2-pyranone (2), and 1-O-(phenylacetyl)glycerol (3), together with known secondary metabolites (S)-4-benzyl-3-oxo-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-6-carbaldehyde (4), (S)-4-isobutyl-3-oxo-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-6-carbaldehyde (5), and the diketopiperazines cyclo(l-Tyr-l-Pro) (6) and cyclo(l-Val-l-Pro) (7), were isolated. ...
Abstract URL:http://pubs.acs.org/doi/10.1021/acs.jnatprod.6b00870
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